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For patients inadequately controlled on 30 to 60 units of basal insulin: Start at 30 units subcutaneously once daily within 60 minutes of the first meal of the day

For instance, a study by Grace et al., on lambs receiving a single 2 mg subcutaneous B12 injection demonstrated significant increases in serum and liver B12 concentrations for up to 24 days compared to untreated animals (2)

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ALF is marked by significant changes in liver function, presenting symptoms such as encephalopathy, coagulopathy, and jaundice in individuals who do not have preexisting chronic liver disease