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NNMT is an enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide (NAM), producing 1-methylnicotinamide (MNA) and S-adenosylhomocysteine (SAH)
More NAD+ boosts SIRT1 activity
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Beyond gastrointestinal effects, injection site reactions (mild redness or tenderness) are occasionally reported but typically resolve within a day
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