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Ingested ARGININE 40% degraded by Intestinal ARGINASE Additional ARGININE DEGRADATION by Enzymes in the blood ARGINASE ARGININE DEIMINASE, ARGININE DECARBOXYYLASE, ARGININE GLYCINE AMIDINOTRANSFERASE Remaining ARGININE Synthesized by NITRIC OXIDE SYNTHASE to Endothelial NITRIC OXIDE The typical American ingests about 4.5 grams of arginine each day

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Using CY 2024 claims data, CPT code 43252 had geometric mean cost of $1,739.85 in the CY 2026 OPPS/ASC proposed rule