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Additionally, Rashmi et al

"Regulation of dopaminergic pathways by retinoids: activation of the D2 receptor promoter by members of the retinoic acid receptor-retinoid X receptor family"

They also found a higher presence of Clostridiaceae bacteria in BD patients, with Collinsella specifically enriched in individuals with BD-II compared to those with BD-I, suggesting that different BD subtypes may have distinct microbiome patterns (McIntyre et al., 2021)

They also reported that feeding studies involving humans and consumption of isothiocyanate-rich cruciferous vegetables have demonstrated measurable Nrf2 activity, reflected in increased levels antioxidant proteins and enzymes, including glutathione S-transferase and NQO1

Excess GSH promotes tumor progression, where elevated levels correlate with increased metastasis

Biochim Biophys Acta Mol Basis Dis (2020) 1866:165747