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This is achieved by the combined inhibition of mechanistic targets of rapamycin complexes 1 and 2 and -catenin by quercetin

This dual citrate sourcing, endogenous mitochondrial production and exogenous uptake, underscores the metabolic adaptability of prostatic cells in maintaining citrate homeostasis for both bioenergetic and biosynthetic demands

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Bioorg Med Chem Lett 2011;21:4674-85