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history of schizophrenia, schizoaffective or bipolar disorder

But animal studies extending up to 6 months show no organ toxicity or adverse histological changes (Sikiric et al., Toxicology and Applied Pharmacology, 2019)

Obesity: Excess body fat, especially abdominal fat, increases insulin resistance and impairs the ability of cells to use insulin effectively, and leads to elevated blood sugar levels

It is not a reason to skip a proper workup for a persistent or worsening problem, and it is not a painkiller you push through a serious injury with

How much weight can I expect to lose