can you take semaglutide with mounjaro vs. Mounjaro: Which works harder for you? Can You Switch From Ozempic

One prime example

Figure 1 4 Metabolic disorders and IBD The prevalence of metabolic disorders, including DM2 and obesity, is increasingly rising in the IBD population

doi: 10.1080/13543784.2018.1471132 266 HaoXZhuXTianHLaiGZhangWZhouHet al

In the SURMOUNT-5 triala head-to-head, open-label, randomized controlled studytirzepatide (Zepbound) was compared to semaglutide (Wegovy) in adults with obesity or overweight and at least one comorbidity (e.g., hypertension, dyslipidemia, obstructive sleep apnea, or cardiovascular disease), but without type 2 diabetes.(11) At maximum tolerated doses over 72 weeks, Zepbound resulted in a mean weight reduction of 20.3%, compared to 13.2% with Wegovy.(11) Patients on the highest dose of tirzepatide and semaglutide reported nausea (31%, 14.4%) and diarrhea (23%, 14%).(9) Tirzepatide is currently the only FDA-approved pharmacotherapy to achieve this level of weight loss

[PMC free article: PMC9996747] [PubMed: 36210202] 39

For non-Medicare patients, the insurance picture is mixed