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In a head-to-head study , semaglutide outperformed liraglutide for weight loss

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However, your doctor must monitor your readings closely during the first 48 weeks because semaglutide can lower blood pressure, potentially requiring dose adjustments to your hypertension medications

GLP-1 enhances insulin secretion in response to oral glucose uptake, thus contributing to the limitation of postprandial glucose increases, 6 but GLP-1 responses are blunted in type 2 diabetes