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In addition, prolonged exposure to pharmacologic doses of long-acting GLP-1 RAs induces tachyphylaxis for the effects on gastric emptying, and that is why nausea vanishes quickly after the beginning of treatment in most patients [19]

Validation of administrative big database for colorectal cancer searched by International Classification of Disease 10th Codes in Korean: a retrospective big-cohort study

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10.1016/s0928-4257(99)00119-9 112 SikiricP.MikusD.SeiwerthS.GrabarevicZ.RucmanR.PetekM.et al (1997b)