Lipid Metabolism and Adipose Biology
I 2 = 0.0%, p = 0.732), HOMA-IR (SMD: 0.73
The authors suggest that this might be because SELECT was designed as a cardiovascular outcomes trial and not a weight-loss trial so those in STEP 1 were desirous of weight loss as a reason for study participation and/or because they received structured lifestyle intervention (which included a 500 kcal per day diet with 150 min per week of physical activity)
Many women get B12 from prenatal vitamins and food, but if you follow a vegetarian or vegan diet, have had GI surgery, or have certain conditions (like pernicious anemia), you might need extra support [*]
Research on GLP-1 receptor agonists like Ozempic and Wegovy concludes there is a risk for increased psychiatric symptoms
At 10 mg/mL, 25 units = 2.5 mg