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Documented observations within controlled laboratory research models Recorded observations in experimental models are primarily associated with glutathione-related redox signaling, oxidative stress markers, and intracellular antioxidant response behavior

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Taken together, these considerations foster the importance of individualizing LT4 replacement therapy, in order to align it not only with biochemical targets but also with the clinical context and physiological nuances of each patient (28)

Radiation therapy can disrupt the normal functioning of these cells, causing them to release an excess of inflammatory cytokines, thereby initiating an inflammatory cascade that results in neuronal tissue damage [182]

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