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Stanley WC, Khairallah RJ, Dabkowski ER

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First, AOD-9604 activates beta-3 adrenergic receptors on fat cells, triggering the cAMP-PKA cascade that activates hormone-sensitive lipase

These findings not only deepen the understanding of the multi-organ protective effects of GLP-1 RAs, but also provide a theoretical basis for the development of MAFLD therapeutic strategies based on multi-target modulation