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However, this association does not imply causationelevated B12 often serves as a biomarker for serious underlying disease rather than being directly harmful

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It is therefore logical that the expression of glutathione-conjugating enzymes including GSTP1 is increased as an adaptive response in drug-resistant tumour cells (Black and Wolf, 1991

Isolation of primary chondrocytes from SD rats and intracellular ROS detection Primary chondrocytes isolated from SD rats using a collagenase digestion method as previously described and cultured in DMEM-F12 medium containing 10% FBS [3]