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Detailed statistical analysis for RNA-Seq, metabolomics, and proteomics are included in Supplemental Methods

CATs have been classified into three groups based on their structure and function: monofunctional heme-containing catalases, heme-containing catalase-peroxidases, and manganese-containing catalases (Glorieux and Calderon 2017)

The decrease of cholesteryl esters in the modified fraction VLDL + LDL caused by L-carnitine suggests changes in fatty acid composition that favor the catabolism of this fraction 15

doi: 10.1016/j.tins.2016.05.002 160 MarinoF.NuceraV.GerratanaE.FiorenzaA.SangariD.MiceliG.et al

They dont directly improve: Irregular cycles Fertility challenges Hair loss or excess hair growth Skin concerns like acne PCOS fatigue or food noise Weight maintenance Your Next Step If youre on GLP-1s (or thinking about them) and want to make sure youre supporting your PCOS too, here are some ways I can help: GLP-1 & PCOS Course (coming soon) Practical steps to support your hormones while on medication

PLoS One 6 (4), e18608