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While dietary interventions emphasizing protein, fiber, and whole foods can improve metabolic parameters and support weight management, the effects are generally more modesttypically 3-5% weight loss and HbA1c reductions of 0.5-1.0% when implemented without other interventions, as seen in programs like the Diabetes Prevention Program

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Although both GSTM2 -overexpressing mice and control mice showed good recovery of hepatic steatosis at 2 weeks, GSTM2 -overexpressing mice showed lower hepatic fat content at 1 week (Fig