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According to Novo Nordisk 's announcement and independent reporting: Clinical Trial Results (OASIS 4): According to the published clinical trial data in the New England Journal of Medicine, oral semaglutide 25 mg taken once daily demonstrated 16.6% mean weight loss when treatment was adhered to in adult participants with obesity or overweight with one or more comorbidities
On the other hand, ferroptosis inhibitors, including ferrostatin-1, iron chelators, and antioxidants, have shown potential in protecting granulosa cells from ferroptosis and oxidative damage, though clinical evidence supporting these strategies is currently lacking
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The new data suggests the problem may be dose-dependent, meaning higher exposure to semaglutide could significantly increase the risk of optic nerve injury
This includes mental health deterioration, memory problems, sensory issues, and sensations of pain
