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Patients with cleft lip and/or palate are not a homogenous group

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Although melatonin treatment was associated with reduced GLUT1 expression ( Figure 5J ), this did not translate into a functional deficit in glucose uptake, as melatonin-treated cells displayed comparable 2-NBDG uptake to controls ( Figure 5K )

Concretamente, parece ser que limita el metabolismo de los lpidos, dando lugar a un incremento en plasma de triglicridos, cidos grasos y cuerpos cetnicos (cidos acetil-actico y -hidroxibutrico), por lo que los aminocidos seran utilizados para satisfacer las necesidades energticas endgenas al estar afectada la disponibilidad de energa no proveniente de las protenas, influyendo en el crecimiento y en la formacin de tejido nuevo 3

doi: 10.1007/s10753-025-02291-8, 73 LukK