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According to the authors, this is the first study to comprehensively compare GLP-1 RAs across pediatric obesity and youth-onset T2DM, integrating potency on efficacy, metabolic effects, safety, and developmental outcomes, while directly contrasting pediatric findings with adult trial data

10.7150/jca.57054 123 ZhangR.PanT.XiangY.ZhangM.XieH.LiangZ.et al (2021a)

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However, these are generally mild and decrease over time