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Furthermore, another study found that the smoke component-induced oxidative damage is greatly reduced by the antioxidant, N-acetylcysteine (NAC) (Huang et al., 2010)

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Next, we found that CXCL10 directly bound to IL18R1 to impair ovarian function through three pathways: inducing ovarian fibrosis through p-JNKp-JUN COL1A1, promoting primordial follicle overactivation through p-AKTp-FOXO3A, and increasing ovarian inflammation through p-P65 IFN