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Its concentration matters, too little and sterility may not be maintained over the full use period, too much and it can interact with the peptide or cause injection site irritation

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Risk of Legal Blindness and Ischemic Optic Neuropathy The GLP-1 cohort had a statistically significant reduction in risk of legal blindness, at all measured time periods, as compared to the control, with a 1-year hazard ratio of 0.589 (95% CI: 0.4760.728), 3-year HR of 0.677 (95% CI: 0.5830.788), and 5-year HR of 0.669 (95% CI: 0.5830.768)