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To test the role of CSF3 in the recruitment of MDSCs in this model, we implanted CSF3-overexpressing (CSF3-OE) 4T1 tumors (Supplemental Figure 3C)

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Inflammatory Response They modulate inflammatory cytokine profiles in the reproductive tract, downregulating proinflammatory mediators like TNF-, IL-6, and IL-1, and sometimes increasing anti-inflammatory cytokines such as IL-10

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