Within the brain, DSIP is particularly abundant in the hypothalamus, hippocampus, and limbic regions, where it interacts with multiple peptide and non-peptide mediators, including corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), and melanin-concentrating hormone (MCH)
Serotonin has long been explored for its potential as an anti-obesity treatment, with a mixed success history, primarily due to troublesome side effects of drugs broadly affecting the serotonin system (4)
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In comparison to diet and exercise alone, GLP-1 drugs can cause people to lose more body fat, but also more muscle mass
[DOI] [PubMed] [Google Scholar] 168.Reiff C.M., Richman E.E., Nemeroff C.B., Carpenter L.L., Widge A.S., Rodriguez C.I., Kalin N.H., McDonald W.M
ScRNA-seq data of the 18-month-old hair follicles were obtained from GSE227784
