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310 Systemic markers of endothelial dysfunction and vascular inflammation are associated with DPN

A history of all prescription and over-the-counter medications should be obtained

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Common triggers include: Large meals High-fat or fried foods Eating too quickly Drinking large volumes with meals Lying down soon after eating Dietitian POV: Who GLP-1s Are (and Arent) For GLP-1s May Be Supportive For: Individuals with insulin resistance or type 2 diabetes Those with obesity who have not responded to lifestyle changes alone Patients with strong medical oversight and nutrition support GLP1s- May Not Be Ideal For: Individuals with uncontrolled GERD or severe reflux history Those with gastroparesis or significant GI motility disorders Anyone unwilling or unable to adjust eating patterns Dietitian Note: GLP-1 success is not just about appetite suppressionits about learning how to eat differently

Developed as type 2 diabetes treatments, glucagon-like peptide-1 (GLP-1) receptor agonists mimic the effects of GLP-1, a hormone produced naturally by the body to regulate hunger and blood sugar

For other weekly GLP-1 agonists like dulaglutide, the standard recommendation is also at least 72 hours between doses