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Hypoxia-induced MMPs can facilitate the breakdown and remodeling of the ECM during wound healing

May help fight against autoimmune disease The chronic inflammation caused by autoimmune diseases can increase oxidative stress

Preclinical testing and species differences Researchers tested Ex-Phe-1 across three preclinical models

Unlike FXa-resistant PAR2-G37I mice, lean PAR2-K36E mice showed no difference in postprandial GIP levels, excluding a role for the matriptase-PAR2 axis in GIP regulation (Figure 1S)

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Individual results vary based on starting weight, diet, exercise habits and other personal factors