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Recent meta-analysis reported that male obesity-secondary hypogonadism (associated with low plasma testosterone and low to normal gonadotrophin concentrations) is observed in almost 33% of men with obesity [9]

For example, inulin supplementation changed the composition of intestinal microbiota, reduced serum levels of uric acid, and increased degradation of fecal uric acid in patients with renal failure (129)

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4 Dual GIPR/GLP-1R therapies improve weight loss by increasing adipose tissue metabolism, such as lipid oxidation and nutrient uptake

the GLP-1 receptor slows gastric emptying and enhances feelings of fullness

PMID: 35 ZhengZZongYMaYTianYPangYZhangCet al