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doi: 10.1016/j.dci.2019.03.009

While GLP-1 receptor agonist therapy leads to greater relative fat loss than lean mass loss, preserving muscle tissue requires adequate protein intake and resistance exercise during weight reduction

Empagliflozin as add-on to metformin in patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled trial

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These divergent effects appear to be modulated by multiple factors, including treatment duration, drug concentration, cancer type, and patient-specific parameters such as genetic background and comorbidities [9, 19]