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In addition to neutralizing oxygen radicals, unconjugated bilirubin also acts as a reducing agent of some peroxides including prostaglandin H synthase (PGH) when in the presence of hydrogen peroxide or organic hydroperoxides (38)

PMID 23602652

Sirt1 and the mitochondria

Another probiotic Lactobacillus casei Zhang significantly upregulated the Bacteroidetes population, a prominent butyrate producer in CKD treated mice (Zhu et al., 2021)