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This review explores the potential changes and mechanisms of the gut microbiota and its metabolites in mediating host adaptation and pathogenesis related to high-altitude exposure, alongside summarizing effective strategies for targeted microbiota modulation to prevent and treat altitude-related disorders

doi: 10.1074/jbc.273.50.33595 Fletcher, Jamie I, Chapman, Bogdan E., Mackay, Joel P., Howden, Merlin E

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