Symptoms associated with B12 deficiency may include: Persistent fatigue or weakness Memory impairment or confusion Nerve-related issues such as numbness or tingling Mood fluctuations or depression Pale or yellowish skin A B12 deficiency can affect anyone, but older adults are particularly vulnerable
Today, Friday, I had another migraine that was not as bad but my heart palpitations and anxiety is at an all time high
Mechanisms underlying neuroprotection include enhanced cerebral angiogenesis supporting tissue oxygenation, anti-inflammatory effects reducing secondary injury, antioxidant activity limiting free radical damage, and modulation of neurotransmitter systems including the dopamine/glutamate/NO system
Vascular and Neurological Research Investigative models involving ischemia or nerve compression may examine whether the peptides, individually or in combination, support microcirculatory perfusion, angiogenic sprouting, or neurotrophic regeneration
That's the manufacturer's guideline and the standard the research community follows
Some people splitting into 2x/week report fewer GI sides, but it's not required