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The normal trachea is cleaned by MUC5B mucin bundles from the submucosal glands coated with the MUC5AC mucin

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HA injections reported that PRP patients had better pain relief and functional improvement at 6 and 12 months post-treatment , whereas HA benefits diminished after 6 months (PMID: 30212925)

Circulating IGF-I deficiency and GH hypersecretion induce insulin resistance which is further augmented by insufficient suppression of hepatic glucose output

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Figure 3 The impact of pyocyanin on mucus hypersecretion is further intensified by its influence on the immune system, particularly by inducing Th2 cytokines secretion, such as IL-4 and IL-13 (194)