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(2015) quantified the difference: 134 nmol of GHK peptide and 705 nmol of copper permeated through microneedle-treated skin over 9 hours

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Vegans, vegetarians, people over the age 50, anyone with stomach/bowel issues like chronic gastritis, leaky gut, IBS or celiac, and anyone who regularly takes medications such as Metformin, PPIs (used for GERD), H2 Receptor Antagonists (used for peptic ulcers), or anything that interferes with stomach acid production are actually at risk for vitamin B12 deficiency, and should supplement B12 regularly

Some common signs of B12 deficiency include: Low energy or fatigue (even after a good nights sleep) Brain fog or memory lapses Mood swings, anxiety, or irritability Numbness or tingling in hands and feet Poor immune function Sound familiar

2022 NEJM)