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Nitric oxide functions both as a signaling molecule in endothelial and nerve cells and as a killer molecule activated by immune cells

So it's often both

Mechanical Symptoms: What They Mean Mechanical symptoms are a red flag for structural damage that may require urgent care: Locking (inability to fully straighten or bend the knee) Catching or clicking during movement Recurrent swelling or giving way These signs often point to a displaced meniscus flap , such as a bucket-handle tear

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