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Patients with early type 2 diabetes managed with diet and exercise only In clinical trials involving patients with early type 2 diabetes who were managed with diet and exercise alone, both oral semaglutide and injection semaglutide demonstrated significant reductions in glycated hemoglobin (HbA1c) levels from baseline

Enhanced Quality of Life: Weight loss can lead to increased mobility, improved self-esteem, and a better overall quality of life

However, these side effects could also contribute to potential malnutrition, due to a reduced ability to consume enough calories and nutrients to meet essential bodily needs

7.2 Integration With Lipid Management Statins, ezetimibe, PCSK9 inhibitors, inclisiran, and bempedoic acid remain foundational therapy for atherogenic-lipoprotein reduction

The two-year data demonstrates that the body does not develop tolerance, the weight does not inevitably rebound while on treatment, and the metabolic improvements persist over the long term