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52 When these stressors become chronic, the HPA axis and the immune system can become dysregulated

10.1007/s11033-025-11273-w 12 ChengQ.ChenM.LiuM.ChenX.ZhuL.XuJ.et al (2022)

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This neuroimmune dysregulation is frequently exacerbated by Mast Cell Activation Syndrome (MCAS), a condition highly comorbid with Long COVID and dysautonomia

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To test this data interpretation, we analyzed the GSSG-dependent oxidation of reduced fusion constructs between roGFP2 WT and wild-type PfGrx (PfGrx WT ), the dithiol mutant PfGrx C88S , or the monothiol mutant PfGrx C32S/C88S (Fig