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In fact, phenomena such as insufficient stability in the stomach, reduced solubility, and hepatic degradation result in a bioavailability of approximately 30% and a short half-life of ALA, whereas intravenous injection of ALA in other models achieves higher bioavailability

Science 206 : 227229

In mouse organoids, the effect of SCFAs was limited to L-cells alone because markers of other endocrine cell types (Sct, Tph, and Gip) remained unchanged

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