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A low eGFR indicates reduced kidney function, which may be due to chronic kidney disease, acute kidney injury, or conditions such as diabetes, high blood pressure, or urinary tract obstruction

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Cell Communication and Signaling, 21 , Article 67

In fact, this double blockage of SGLT1 and GLUT2, completely inhibits the responsiveness to other stimulants as well, such as sucralose, glycylsarcosine, OEA, propionate and taurocholate