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One review of this interaction recommends that individuals consuming 2 grams per day or more of acetaminophen for 3 or more consecutive days should have their monitoring of warfarin increased 3 to 5 days after the first dose of acetaminophen

Liu J, Song L, Liu S, Zhao S, Jiang Q, Ding B

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DOI: 10.1007/s00213-021-05986-6

PMID: 10754513

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