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Current in vitro experimental results suggest that a high concentration of synthetic AST (20 mol/L) can enhance cellular antioxidant capacity by inducing PON1 [72]
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These models evaluate multiple antioxidant mechanisms, including ROS scavenging, antioxidant enzyme activation, and cytoprotective effects, bridging the methodological gap between chemical assays and complex in vivo studies (Meng et al., 2017)