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Treatment-nave patients saw a median DoR of 13.4 months with a 78% ORR, while patients previously treated with platinum-based chemotherapy had an ORR of 63% and DoR of 38.8 months

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doi: 10.1016/j.jneuroim.2019.03.012 78 KurutasE

Xu P, Qiao K, Stephanopoulos G (2017) Engineering oxidative stress defense pathways to build a robust lipid production platform in Yarrowia lipolytica

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However, increased exposure to thiocyanate ions from cruciferous vegetable consumption or, more commonly, from cigarette smoking, does not appear to increase the risk of hypothyroidism unless accompanied by iodine deficiency