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Animal Model:High fat diet-induced obesity mouse model [3] Dosage:50 mg/kg Administration:i.p., twice per day for 28 days or 12 days Result:Did not alter brown adipose tissue mass, daily food intake and glucose metabolism, increased fatty acid oxidation (FAO) in normal in C57Bl/6 mice, but induced a progressive weight loss and decreased adipocytes size in high fat diet-induced obesity mouse models

Mixed axonal-demyelinating: Most common pattern in chronic polyneuropathies

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The administration of Fer-1 markedly prevented ultrastructural and morphological alterations in Raji cells, such as increased density of mitochondrial membranes and incomplete mitochondrial cristae, in Raji cells (Fig

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They fall instead under the general remit of the Human Medicines Regulations 2012, which is why unlicensed injectable preparations cannot lawfully be supplied for human administration regardless of "research use only" labelling [3][4]