Pathological causes of elevated B12 warrant careful consideration: Haematological disorders : Myeloproliferative neoplasms (polycythaemia vera, chronic myeloid leukaemia), acute leukaemia, and lymphoproliferative disorders can increase B12-binding proteins (transcobalamin and haptocorrin), elevating total serum B12 [3] Liver disease : Hepatocellular damage releases stored B12 into circulation
Megaloblastic anemia is one such deficiency, a macrocytic anemia that causes bone marrow to create very large red blood cells
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The dosage strength and treatment frequency also play a role in overall expenses, which can be determined during a personal consultation
For non-emergency concerns such as persistent injection site reactions or new neurological symptoms, contact your GP or NHS 111