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We also observed upregulation of mesenchymal markers ( VIM and TWIST ) and downregulation of epithelial markers ( CDH1 , CLDN7 and TJP3 , Figures 2F, G ) , consistent with earlier observations in other persister cell models ( Figure 2 CRC Persister Cells Are Vulnerable to Ferroptosis To effectively eliminate CRC DTP cells, we sought to identify therapeutic vulnerabilities in persister cells that are absent in parental and regrown cells

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Hamilton Depression Rating Scale (HDRS), 23 Beck Depression Inventory (BDI), 24 and Montgomerysberg Depression Rating Scale (MADRS) 25 as standardized mean differences (SMDs) and their corresponding 95% CI at end-of-treatment (negative values favor ALC) using random-effects (REML) models

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