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GLP-1R is present in the human choroid plexus, where GLP-1R analogs reduces cerebrospinal fluid secretion and intracranial pressure by increasing the intracellular concentration of cyclic adenosine monophosphate and inhibiting the Na + /K + ATPase pump in the choroid plexus [25]

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Identification of this gene as top interactor can explain the potential side effects of GLP1RA in our study, like alterations in behavior, enrichment of Parkinsons disease