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Following administration of 0.25 mg digoxin concomitantly with 100 mg of sitagliptin daily for 10 days, the plasma AUC of digoxin was increased by 11%, and the plasma C max by 18%

TT: Conceptualization, Formal Analysis, Methodology, Project administration, Supervision, Writing review and editing

Always check with a pharmacist before adding supplements, especially when on prescription injections

Injectable semaglutide formulations also delay gastric emptying but have not been studied as formally for levothyroxine interaction

Mahajan, A., et al

Bottom line: Stick to simple, clean preparations like sashimi or basic rolls without fried ingredients or heavy cream-based sauces to minimize the risk of stomach upset