Furthermore, we observed that the expression of multiple NRF2 target genes responsible for maintaining cellular redox balance (for example, NQO1 , PRDX1 , OGGIN1 , HMOX1 , KEAP1 and SLC3A2 ) increased following mut-p53 knockdown and decreased with mut-p53 overexpression (Supplementary Fig
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These findings may be relevant to human disease
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