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They followed this with a metaanalysis, which pools the results of multiple studies to estimate an overall effect

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The post lists fasting insulin, HbA1c, liver enzymes, renal function and baseline GLP-1 levels as the values that give clinical context for whether 5 mg is an appropriate starting point

Your healthcare provider can help you weigh these risk factors against the potential benefits to determine if these medications align with your health goals

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Additional evidence included in this review were from a longer-term placebo-controlled trial that was non-pivotal (STEP 5, 104 weeks) as well as a sponsor-submitted ITC