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As the second most common neurological disease, approximately 6,200,000 people around the world were suffering from PD in 2015, and the prospective number of PD patients keeps growing (Vos et al., 2016

Excessive ROS production not only impairs cellular function but also activates primordial follicles, potentially leading to depletion of the ovarian follicle reserve through the inhibition of PTEN and subsequent activation of Akt pathways (70)

Chen J, Fan X, Zhou L, Gao X

Anaplerotic diet therapy in inherited metabolic disease: therapeutic potential

It serves as a foundational component for mitochondrial function, cellular energy production, cellular DNA repair, and the regulation of systemic inflammatory pathways

Matveyenko, A