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NICE guidance (NG28) specifies that these agents should generally be considered in people with a BMI 30 kg/m (or lower in certain ethnic groups) and specific problems associated with high weight, or if insulin would have significant occupational implications

Reece EA, Leguizamon G, Homko C

Developmental changes of glutamate and GABA receptor densities in wistar rats

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Mitochondria-targeted antioxidants, including MitoQ and SS31, may serve as potential therapeutic agents that reduce free radicals, maintain mitochondrial quality and function, enhance autophagy and mitophagy, and help cells remove damaged mitochondria [24, 31]