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Wolf, K., Alexander, S., Schacht, V., Coussens, L

This question concerns many patients considering or currently taking this dual GIP/GLP-1 receptor agonist for type 2 diabetes or weight management

After 48 hours, heat therapy (warm compress or bath) promotes blood circulation and accelerates reabsorption of bruised tissue

Our study has several limitations

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Moreover, GLP-1R antagonism partly reduced plasma TGs and this effect could be explained by the GLP-1R-mediated insulin secretagogue effect of G49 that likely accounts for insulin-mediated de novo lipogenesis rather than a direct effect of G49 actions in the liver through the GLP-1R which is nearly absent as reported 54