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These modifications may include the Vssc mutation, insensitivity of synaptic acetylcholinesterase (AChE1) and mutation in the GABA receptor [56]

The mechanism of action of peroxide antimalarials involves the reductive activation of the peroxide bond by intra-parasitic haem, but there is no consensus regarding the specific protein targets of the resulting radical species for artemisinins and/or the ozonides

J Neurosci 16 : 31233129

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GCMS, Gas ChromatographyMass Spectrometry

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